Histopathological features of chronic hepatitis B reactivation

Reactivation of hepatitis B.

Reactivation of hepatitis B refers to the abrupt increase in hepatitis B virus (HBV) replication in a patient with inactive or resolved hepatitis B. Reactivation can occur spontaneously, but more typically is triggered by immunosuppressive therapy of cancer, autoimmune disease, or organ transplantation. Reactivation can be transient and clinically silent, but often causes a flare of disease tha...

liver histopathological features of hbeag-negative chronic hepatitis b in young bangladeshis

Treatment of Chronic Hepatitis B with Tenofovir

Background:Tenofovir is among the first-line treatments for chronic hepatitis B (CHB) virus infection. We evaluated the efficacy of Tenofovir in the treatment of Iranian adult patients with CHB. Methods: In a retrospective study, we evaluated 154 HBsAg positive patients referred to Sadoughi hospital in Yazd-Iran for treatment ...

Fatal hepatitis B reactivation following discontinuation of nucleoside analogues for chronic hepatitis B.

BACKGROUND Nucleoside analogues such as lamivudine for chronic hepatitis B have an excellent safety profile while patients are on therapy but reactivation flares occur in 19-50% of patients after stopping therapy, some of whom develop liver decompensation. AIMS To describe and report three cases who developed fatal hepatitis B reactivation after stopping nucleoside analogue therapy. SUBJECT...

Chronic hepatitis B reactivation and systemic glucocorticosteroid therapy.

SIR, We read with interest the article by Yang et al. in a recent issue of the Journal in which they retrospectively reviewed patients with pemphigus vulgaris and dermatomyositis treated with immunosuppressive therapies including systemic glucocorticosteroid (GC). In the article, the authors suggested that four of 98 patients had developed hepatitis because of GC-induced hepatitis B virus (HBV)...